Systems Biology Research Group
- The Bioinformatics research group is hosted in the Centre for Molecular Biosciences at Coleraine Campus
Introduction
The Systems Biology Research Group of the University of Ulster is located at the Centre for Molecular Biology, Coleraine. The Group’s vision of future biological research is strongly influenced by systems biology as the key conceptual framework for significant progress in post-genomic biology. For a schematic overview, see the following figure originally published by Kitano in Science, 2002 (Systems Biology: A Brief Overview):
Research Objectives
Systems biology research complements the University’s ongoing biological research, which includes proteomics, genomics, biotechnology, and other areas.
- 3D reconstruction of biological images from microscopy
Methods in these fields are characterized by enormous quantities of complex-structured digital data that require carefully tailored information processing before they can be interpreted.
The main objective of the Systems Biology Research Group is to develop novel and adapt and apply existing bioinformatics and systems biology methodologies, tools and systems.
As biological phenomena are being probed and mapped in ever-greater detail, biologists from a wide range of subdisciplines are facing an exponentially growing volume of increasingly complex-structured data, information, and knowledge.
A fundamental challenge for bioinformaticians and computational biologists is to explore, manage, share, analyse and interpret this information effectively and efficiently. The Systems Biology Research Group was established to address this challenge.
The Group’s vision is strongly influenced by systems biology as a framework for biology in the post-genomic era. Currently, the Group is engaged in a number of research projects in areas such as the
Application and development of analysis and interpretation methods for biological data using machine learining and statistics,
Application and development of methods for integrating, managing, and sharing of biomedical information using database, data/text mining, data warehousing, and grid technology,
Application and development of methods for processing of image data (e.g. from microscopy) an for modeling of computational geometry of biological structures and processes,
Application and development of methods for system-level modelling and simulation (e.g., gene networks, kinase/phosphatase interaction networks, protein unfolding simulations),
Application and development of methods for predicting subcellular localization of various biochemical entities,
Application and development of methods for analysis and interpretation of scientific articles and texts using text mining and natural language processing,
Application and development grid technologies in biology and Systems Biology.
Projects
Current projects of the Systems Biology Research Group
Teaching
Systems Biology and Bioinformatics Teaching
Presentations
pdf presentations given by group members
Unclassified
articles that do not go into any other section go there (eg news articles, personal pages, ...) also contains attached images and documents for the whole site
Bioinformatics and Systems Biology at the University of Ulster